Healing has to be interrupted till these consequnces have disappeared, after which treatment has to be followed at a lower dose.
Hoarseness of the voice may be the first symptom of vocal change which can lead to irreversible lowering of the voice. In case signs of virilisation advance, particularly lowering of the voice, treatment must be stopped unless the consequnces are desired management outcomes.
The following negative effects have also been known:
– disorders of liver function
– weight put (in female-to-male transsexuals)
According to the aggregate data from a number of scientific studies, despite its conservative nature, Primobolan was proven to provide significant increases in muscle development in a reasonable amount of time. Another interesting fact that was discovered during the testing of this compound was the fact that it effectively bound itself to the AR. In fact, Primobolan was able to bind itself to the AR more effectively than naturally produced testosterone. This is huge because the ability to effectively bind to the AR allows Primobolan to be one of the most effective fat-burning compounds available. Positive AR binding has been directly correlated with lipolysis.