The common dose for Dianabol is 30-50mg each day , with a cycle that would usually last between 4 and 6 weeks . 30-40mg would be an effective dose for a person that is new to Dianabol, resulting in great gains in muscle mass and strength, whilst restricting possible side effects. More experience users may wish to take a slightly higher dosage, although like most other compounds, there is a dosage level where the muscle and strength gains plateau off and the side effects heighten, resulting in a point in which it is not worth increasing the dosage. Most experienced users will rarely take a dosage over 70-80mg per day.
After the Kefauver Harris Amendment was passed in 1962, the . FDA began the DESI review process to ensure the safety and efficacy of drugs approved under the more lenient pre-1962 standards, including Dianabol.  In 1965, the FDA pressured CIBA to further document its legitimate medical uses, and re-approved the drug for treating post-menopausal osteoporosis and pituitary-deficient dwarfism .  After CIBA's patent exclusivity period lapsed, other manufacturers began to market generic metandienone in the .